Book of Abstracts: Albany 2009

category image Albany 2009
Conversation 16
June 16-20 2009
© Adenine Press (2008)

Genome-wide mapping and analysis of nucleosome positions in multiple human tissues

Nucleosome positioning plays a fundamental role in the regulation of the genome. To further explore the relationship between the underlying DNA sequence, chromatin architecture and genic expression in differing tissues, we have mapped nucleosome positions across three separate human tissue types from the same individual and analyzed these data in relation to the genic landscapes and regulation in these distinct cell types.

Steve M. Johnson*
Anton Valouev
Scott Boyd
Cheryl Smith
Arend Sidow
Andrew Fire

Departments of Pathology and Genetics
Stanford University School of Medicine
Stanford, CA 94305
* current address:
Department of Microbiology and Molecular Biology
Brigham Young University
Provo, Utah 84602

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