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Book of Abstracts: Albany 2009

category image Albany 2009
Conversation 16
June 16-20 2009
© Adenine Press (2008)

Unique Correlation Patterns of Sequence Repeats and Splice Junctions in Eukaryotic Protein Sequences

Analysis of eukaryotic protein sequences demonstrates that short sequence repeats (homopeptides) are not distributed evenly along eukaryotic genes, but rather display unique correlation patterns relative to the splice junctions of those genes. This phenomenon sheds new light on the evolution of eukaryotic genes and the splicing patterns. Interestingly, the most frequent repeats involve the most ancient amino acid residues, according to temporal order of appearance of various amino acids in early evolution[1].

References and Footnotes
  1. Trifonov, E. N. The Triplet Code From First Principles. J Biomolec Str Dyn 22, 1-11 (2004)

E. Aharonovsky
E.N. Trifonov*

Genome Diversity Center
Institute of Evolution
University of Haifa
Haifa 31905, Israel

Tel. : +972-4-8288096
Fax : +972-4- 8246554
trifonov@research.haifa.ac.il