Albany 2005: Conversation 14
June 14-18 2005
Topics, Speakers, Chairs and Guests
Albany 2005, The 14th Conversation, June 14-18, 2005 will be staged at the State University of New York, Albany, NY 12222 USA. Delegates arrive on Tuesday June 14th, dinner and reception that evening, and the scientific program starts on June 15th, Wednesday morning. The program will end on Saturday June 18th at 2:00 PM after lunch. The conference roughly has about 50 lectures by leading scientists, in addition to several short lectures by young scientists who are selected from abstracts submitted for poster presentation. We display at the same time some 250 poster discussion papers. We anticipate about 400 delegates of diverse background from over 20 countries for these continuing conversations.
Young Scientist Lecture Program
The Organizing Cmte has left unfilled 5.5 hrs of the Conversation time for the young scientist lecture program. Professionally young researchers at the rank of assistant professors, post-doctoral fellows and graduate students, will be selected to provide oral presentations from the abstracts submitted for poster presentation.
Albany Conversation traditionally holds long evening lectures in areas of fundamental interest to structural biology. This year, on Wednesday June 15th 8:00 PM, Harold Scheraga, Cornel Univ., will provide a tour de force overview of protein folding, visiting the historical transformation from experimental science to theoretical realms; he will discuss theoretical formalisms to delineate protein structure with illustrations of performance in successive CASP blind tests. Thursday at 8:00 PM, Koji Nakanishi, Columbia Univ., will elaborate on the bioorganic chemistry of vision. Rhodopsin is the pigment responsible for vision and is the most studied of the numerous G-protein coupled receptors (GPCR) that are involved in about half of all drugs being sold or developed by pharmaceutical companies. Barry Honig, Columbia Univ., will chair the session and introduce the evening speakers.
Proteins: Design, Interactions & Aggregation
Design, protein-protein interactions and aggregaton are currently a central theme in protein science. One can in principle design ab initio a protein to deliver a desired function. The ability to design an enzyme to perform a given chemical reaction has considerable practical application for industry and medicine. Significant progress has been made at enhancing the catalytic properties of existing enzymes; protein design techniques have been employed to increase the effectiveness of antiviral peptides in binding the HIV protein gp41. Understanding and ultimately predicting protein association is immensely important in functional genomics and drug design. We will examine the current perspective of protein design, protein-protein interactions, predicting the association geometry and induced fit in protein docking, and in particular the application of these to predict protein-protein interactions towards Systems Biology. We shall explore the wrapping concept in protein structure, examining its importance for network centrality, interactome evolution, molecular disease and aberrant aggregation. In addition to high end theoretical exploration, we present crystallographic data on a new chaperone protein, shaped like a jellyfish with dynamic tentacles to bind to lots of different proteins. This evolving story is told by: Ariel Fernandez, Rice Univ., Ruth Nussinov, NIH and Tel Aviv Univ., Ruben Abagyan, Scripps, Steven L Mayo, Caltech and Marcelo C. Sousa, Univ. of Colorado.
DNA Targeting: Molecular Design & Recognition
Since Peter Dervan, Caltech, delivered the evening address in 1997 during the 10th Conversation, there have been immense progress on molecular design for DNA recognition. For this 14th Conversation, Dervan will report on the advances in the design of programmable small molecules which bind DNA sequence specifically and are cell permeable and on his efforts to modulate the transcription of endogenous genes in cell culture. Bruce Armitage, Carnegie Mellon Univ., proposes a new strategy for nucleic acid recognition: homologous hybridization between guanine-rich peptide nucleic acid (PNA) probes and DNA/RNA targets. Steve Rokita, Univ. of Maryland, has developed a general strategy for site-directed alkylation of nucleic acids. This utilizes a safety-catch mechanism that prevents release of a reactive component prior to target association. Hiroshi Sugiyama, Kyoto University, Japan, will talk about a rational design of sequence specific DNA alkylating agent as a tailor made antitumor agent.
DNA in a bacterial virus is in tight squeeze, and this confinement involves large forces requiring the active participation of protein motors. Rob Phillips, Caltech, will elaborate on this theme, from mechanical engineering and physics perspective. Diana Murray, Weill Medical College of Cornell, shows that calculations with atomic models of viral proteins and phospholipid membranes provide insight into the assembly of retroviruses. Avinoam Ben-Shaul, Hebrew Univ., Jerusalem, Israel, takes up the question of the structure and energetics of polynucleotide packaging in viral capsids. Fred Dyda, NIH, talks on the Adeno-Associated Virus (AAV), the small DNA virus that is frequently employed as a gene transfer system in gene therapy. He employs x-ray crystallography to map the initiator assembly of AAV.
DNA and Beyond
In mammals PKR kinase acts in the interferon response to phosphorylate an initiation factor, and thereby stops protein synthesis. It contains double stranded RNA binding domain as well as kinase domains. Alex Rich, MIT, has discovered that zebra fish has PKR activity, but the protein does not contain double stranded RNA binding domain, but, instead, has substituted it with Z-DNA (Z-RNA) binding domain. It has the same physiological activity and phosphorylates the same initiation factor leading to cessation of protein synthesis. Dale W. Wigley, Clare Hall Labs, London, UK, summarizes his studies using x-ray crystallography and enzymology on the mechanism of several helicases which perform such tasks as simple strand separation & more sophisticated processes in repair and recombination. Modesto Orozco, IRBB-PCB & University of Barcelona, Spain, will lecture on the multi-dimensional nature of the modelling of biomolecular systems with nucleic acids as example.
Evolution: Early & Directed
Visiting the past and transporting to the future border on Divinity. We do this in Albany to energize the intellect and pay homage to our ancestral genes. Paul Schimmel, Scripps, explores the origin of human diseases. In the early development of the genetic code, statistical proteins were prominent. Experiments creating statistical proteins from a more primitive code yield phenotypes in mammalian cells that could explain the origin of some human diseases. Charlie Carter, Univ. of North Carolina, propounds the idea that amino acid activation is probably the earliest "biological" function and that the two classes of synthetases may have arisen together from the same primordial gene. Apart from early evolution, now-a-days molecular evolution can be directed in the test tube in order to produce useful biocatalysts. Linda Castle, from Pioneer, a plant genetics house of duPont, will talk about the discovery and development of a must have detoxification trait in agriculture today.
Comparative Genomics; Central Machinery of Life
Comparative analysis of multiple genome sequences from various walks of life allows us to discover and quantitatively characterize fundamental features of biological evolution that have not been apparent in the pre-genomic era. We discover horizontal gene transfer, selective loss of a gene and gene classes, rise and fall of genome complexity, and unexpected dynamics of amino acid composition of proteins which might shed light on the evolution of the genetic code. A combination of comparative genomics techniques, including functional and genome context analysis, allows us to infer novel functional variants of central metabolic subsystems and tentatively identify presently unknown (missing) genes, for example several tRNA modification gene families, involved therein. The subject will be covered by Eugene Koonin, NIH, Andrei Osterman, The Burnham Institute, and Valerie de Crecy-Lagard, Univ. of Florida.
Repair Machines, Mechanism & Nucleotide Flip
John Tainer, Scripps, advocates that protein machines assembled in response to DNA damage employ common elements: DNA minor groove binding and bending, dynamic assemblies, interface mimicry and exchanges, plus protein conformational change linked to DNA and/or ATP binding. Michael G. Fried, Univ. of Kentucky, elaborates on lesion-search mechanism of Human O6-Alkylguanine DNA Alkyltransferase (AGT). It is surprising that AGT lacks significant sequence- and lesion-binding specificities. Norbert Reich, Univ. of Califoria, Santa Barbara, will lecture on the mechanisms of protein-induced base flipping, and its importance to catalysis, specificity, and the development of therapeutics based on inhibiting the target enzymes. Olga Fedorova, Russian Acad. of Sciences, will devote on multiple conformational changes in DNA repair enzymes during substrate recognition and processing with particular reference to 8-oxoguanine DNA glycosylases.
Small RNAs: Riboswitches and siRNA
Riboswitches are genetic regulatory elements found in mRNAs that directly bind small molecule metabolites and effect transcription or translation through allosteric changes in RNA folding, complex structural and functional features. Ronald R. Breaker, Yale Univ., describes several new riboswitches. One class of riboswitch has recently been identified that uses the action of a ribozyme to cleave the messenger. Another class binds two ligands cooperatively to create a more "digital" genetic switch. He demonstrates that RNA can perform complex gene control tasks that had previously been observed only with protein factors. Robert T. Batey, Univ. of Colorado, describes the first high resolution crystal structure of a hypoxanthine riboswitch where the RNA fold completely envelops the ligand. Lucy Malinina, Sloan Kettering, dwells on small interference RNA and explores the structural principles of small RNA duplex recognition from two recent crystal structures of complexes between protein p19 and small interfering 21nt RNAs.
Large RNAs: Intron and Spliceosome Structural Dynamics
High resolution x-ray crystallography is used to understand the role of RNA in facilitating the chemistry and dynamics of RNA self-splicing. The intron uses unprecedented RNA structural motifs to select the 5'- and 3'-splice sites. It uses its phosphate backbone to coordinate active site metal ions in the same manner that a protein uses the side chains of aspartates and/or glutamates. Scott Strobel, Yale Univ., and Barbara Golden, Purdue Univ., will reveal the intron story. Reinhard Luehrmann, MPI, Goettingen, Germany, presents the structural dynamics of spliceosome, a large molecular machine consisting of the snRNPs U1, U2, U4/U6 and U5 and more than 150 non-snRNP splicing factors. This machine undergoes multiple structural rearrangements during pre-mRNA splicing. Luehrmann charts the dynamics of the RNA-RNA, RNA-protein and protein-protein network of the spliceosome during its action cycle.
The pioneer in the discipline Ned Seeman, New York Univ., presents a complement of four young investigators. Seeman has demonstrated supramolecular self-assembly of DNA and its control at the nanometer scale. The essential concept is to construct well-defined structures by integration of stiff branched DNA motifs and predictable intermolecular interactions. Building on previous work, Chengde Mao, Purdue Univ., has designed and assembled various DNA nanostructures, and has further transferred such structures into metallic motifs. Taking it a step further, Niles A Pierce, Caltech, will discuss engineering DNA motors and sensors. Paul Rothemund, Caltech, enters the imaginative realm of complex and interesting pattern creation by algorithmic self-assembly. He will discuss the state of the art in algorithmic self-assembly and the creation of templates to nucleate them, and how one can augment the complexity of self-assembled patterns. William M. Shih, Harvard Univ., takes up clonable DNA nanotechnology. A key property of DNA ? its ability to be amplified exponentially by polymerases ? facilitates the large-scale clonal production of individual sequences. Previous examples of three-dimensional geometric DNA objects, however, were built using architectures that are not amenable to copying by polymerases. Shih has developed a strategy for encoding DNA cages as single strands that are amplifiable by polymerases; his demonstration of a clonable DNA octahedron represents a large step toward making the use of DNA scaffolds more practical and more versatile.
DNA Bending & Torture
Jonathan Widom, Northwestern Univ., has discovered that DNA spontaneously forms sharp loops with a probability that exceeds theoretical expectation by as much as 100,000-fold. The twistability of DNA in this regime is far greater than predicted. There is a need for new theories of DNA bending. Alexey Mazur, IBPC, Paris, France, takes up nicked A-tracts & compressed backbone hypothesis which results in geometric frustration & other unusal physical properties. Mazur offers new interpretations. Maxim Frank-Kamenetskii, Boston Univ., discusses kinking of nicked DNA. He derives thermodynamic stability data for the equilibrium between stacked and kinked conformations. Tom Tullius, Boston Univ., tortures DNA by chopping it up with the hydroxyl radical. He uses the pattern of DNA strand breaks to make a map of the structure of DNA in the genome.
DNA Looping and Bacterial Chromosomal Structure
One of the important elements in the formation of the bacterial chromosome (or nucleoid) is the strong compaction of the single, circularized DNA molecule comprising the genome. In bacteria such as E. coli, this compaction is of the order of 1000 times. A group of about ten different proteins collectively referred to as "nucleoid-associated" contribute to the compaction and folding of the genome, in addition to many important roles they play in DNA commerce such as the control of gene expression and replication, through the formation of high-order architectural complexes and loops. Remus T Dame, State Univ., Amsterdam, The Netherlands, discusses the looping of DNA by nucleoid-associated proteins. Such looping is the raison détre for DNA compaction/organization and transcription regulation. Joel Stavans, Weizmann Institute, Rehovot, Israel, presents results of experiments in which the elasto-mechanical properties of individual complexes formed between nucleoid-associated proteins and DNA have been probed, using single molecule elasticity and fluorescence resonance energy transfer techniques. Sankar Adhya, NIH, will focus on assembly and stability of gene regulatory nucleoprotein complexes in the bacterial chromosome. N. Patrick Higgins, Univ. of Alabama, will describe new techniques that show how chromosomal domains in bacteria are reorganized by the process of transcription. Michael Tolstorukov, NIH, will describe how non-random clustering of A-tracts in genome may facilitate DNA looping and non-nucleosomal condensation in bacterial nucleoid.
Expandable Repeats, DNA and RNA Structures, and Human Disease
The expansion of unstable microsatellites has been linked to a number of inherited neurological and neuromuscular diseases. This is a genetic instability of trinucleotide repeat sequences, and can be considered to be some form of mutation responsible for at least 16 diseases including Huntingtons disease and myotonic dystrophy. Within families affected by fragile X, for example, symptoms such as learning difficulties grow increasingly severe and show up earlier in life with each successive generation. This phenomenon is called genetic anticipation. Mutation events are likely to involve slipped-strand DNAs formed by out-of-register mispairing at the repeats. Christoper E. Pearson, The Hospital for Sick Children, Toronto, Canada, will lecture on processing of slipped-strand DNA structures formed by disease-associated trinucleotide repeats. Structural features of slipped-strand DNAs, including the slip-out sequence and the slip-out junctions can critically determine the manner in which these mutagenic intermediates are processed by human cellular proteins, the outcome of which can affect genetic instability. Cynthia T. McMurray, Mayo Foundation, dwells on hijacking DNA repair enzymes which causes CAG expansion. Guy A. Rouleau, Montreal General Hospital, Montreal, Canada, presents his work aimed at understanding the mechanism whereby CAG tracts promote frameshifting, as well as the possible role of such events in human disease. Maurice S. Swanson, Univ. of Florida, elaborates on microsatellite expansion diseases that are caused by the production of toxic RNAs.
Speakers, Chairs and Guests
Abagyan, Ruben, Scripps
Adhya, Sankar, NIH
Aharonovsky, Elik, Univ. of Haifa, Haifa, Israel
Amosova, Olga, Princeton Univ.
Andrianov, Alexander M, NAS, Belarus
Armitage, Bruce, Carnegie Mellon Univ.
Arnott, Struther, Imperial College, London, UK
Augustyn, Katherine, CALTECH
Babayan, Yuri., Yerevan State Univ., Armenia
Barvik, Ivan. Jr., Insti. Physics, Prague, Czech Republic
Bat, Olga, Univ. of Texas
Batey, Rob, Univ. of Colorado
Bayrer, James, Case Western Reserve
Ben-Shaul, Avinoam, Hebrew Univ., Jerusalem, Israel
Belostotsky, Dmitry., State Univ. of New York, Albany
Belotserkovskii, Boris., UC Berkeley
Besschetnova, Irina, RAS, Moscow, Russia
Beveridge, David, Wesleyan Univ.
Bishop, Thomas., Tulane & Xavier Universities
Breaker, Ron, Yale Univ.
Bolshoy, Alexander., Indiana Univ
Boyajyan, Zaryhi, Yerevan State Univ., Armenia
Brahmachari, Samir., IGIB, CSIR, Delhi, India
Britchi, Alina., Wesleyan Univ.
Carter, Charlie, Univ of North Carolina
Castle, Linda, Pioneer, a duPont company
Chakraborty, Banani, NYU
Chattopadhya , Jyoti, Univ. of Uppsala, Sweden
Cheatham, Thomas, Univ. of Utah
Chen, Congju., Wesleyan Univ.
Chen, Siying., Wesleyan Univ.
Cho, Bongsup, Univ. of Rhode Island
Coman, Daniel., Yale Univ.
Coman, Maria, Wesleyan Univ
Constantinou Pamela E, NYU
Cunningham, Richard, State Univ. of New York, Albany
Czapla, Luke., Rutgers Univ.
Dame, Remus, State Univ. Amsterdam, The Netherlands
Danilov, Victor, NAS, Ukraine
Dasgupta, Dipak, Saha Insti. of Nuclear Physics, Kolkata, India
de Crecy-Lagard, Valerie, Univ. of Florida
Derbyshire, Vicky., Wadsworth Center
Dervan, Peter, CALTECH
DeRosa, Maria., Caltech
Diep, Truc., Boston Univ.
Ding, Baoquan, NYU
Ding, Liang, NYU
Dong, Guangcheng., Boston Univ.
Doris, Rosemarie, Wesleyan Univ.
Douglas, Kenneth, Univ. of Manchester, UK
Du, Quan, NYU
Duax, William, L., Hauptman-Woodward MRF, Buffalo
Dyda, Fred, NIH
Every, Alicia., Wesleyan Univ.
Fedorova, Olga, Russian Acad. of Sciences
Fernandez, Ariel, Rice Univ.
Frank, Joachim, Wadsworth Center
Frank-Kamenetskii, Maxim, Boston Univ.
Frenkel, Zakharia, Univ. of Haifa, Haifa, Israel
Fried, Michael, Univ. of Kentucky
Gabdank, Idan, Gurion Univ. of Negev, Israel
Gabrielian, Anna, NAS, Armenia
Gao, Haixiao, Wadsworth Labs
Gao, Ning., Wadsworth Labs
Garibotti, Alejandra V, NYU
Gay, Timothy., Boston Univ.,
Gmeiner, William, Wake Forrest Univ.
Golden, Barbara, Purdue Univ.
Greenbaum, Jason., Boston Univ.
Haran, Tali, Technion, Israel
Harris, Lester F., Hickok Cancer Res. Lab
Heinemann, Udo, MDC fuer Molekulare Medzin, Berlin, Germany
Hennemuth Brad, Univ. of Mass. at Lowell
Higgins, Pat, Univ. of Alabama
Hiraga, Kaori., Wadsworth Center
Honig, Barry, Columbia Univ.
Huether, Bobby., Hauptman-Woodward MRF, Buffalo
Hui-ying, Yang, Sun Yat-Sen Univ., Guangzhou, P R China
Israel, Lisa, NYU
Ivanov, Valery, Russian Acad, of Sciences
Jain, Swapan, Georgia Tech
Jernigan, Robert, Iowa State Univ.
Jiang, Lihong., Yale Univ.
Johnson, Clifford, NYU
Kabanov, A. V., RAS, Pushchino, Russia
Karpova, Elizaveta, Russian Acad. of Sciences, Moscow, Russia
Knee, Kelly., Wesleyan Univ.
Kogan, Simon, Univ. of Haifa, Haifa, Israel
Koonin, Eugene, NIH
Kopatsch, Jens, NYU
Kormos, Bethany., Wesleyan Univ.
Koval, Vladimir, Academy of Sciences, Novosibirsk, Russia
Kozobay-Avraham, Limor, Univ. of Haifa, Israel
Krueger, Andrew, Boston Univ.
Kuhn, Heiko., Boston Univ.
Kurita, Noriyuki., Toyohashi Univ. of Tech., Toyohashi, Japan
Kuryavyi, Vitaly., Sloan Kettering
Li, Jeff., Harvard Univ.
Li, Yan, NYU
Liang, X. G., Boston Univ.
Liang-nian, Ji, Sun Yat-Sen Univ., Guangzhou, P R China
Liao, Shiping, NYU
Lilley, David, Univ. of Dundee, UK
Liu, Chunhua, NYU
Luehrmann, Reinhard, MPI, Goettingen, Germany
Malinina, Lucy, Sloan Kettering, New York
Manrao, Suraj., Spectra Stable isotope, Columbia MD
Mao, Chengde, Purdue Univ.
Marky, Luis., Univ. of Nebraska Med. School
Marx, Kenneth, Univ. of Mass. at Lowell
Mayo, Steven, CALTECH
Mazur, Alexey, IBPC, Paris, France
McMurray, Cynthia, Mayo Foundation
Meister, Walter-Vesely, Germany
Mirkin, Sergei, Univ. of Illinois, Chicago
Morozov, Vladmir, Yerevan State Univ., Armenia
Murray, Diana, Weill Medical College of Cornell
Nakanishi, Koji, Columbia Univ.
Narang, Pooja, IIT-Delhi, India
Nelson, Don., Clark Univ.
Nielsen, Katrine., Univ. Southern Denmark, Odense, Denmark
Niu, Li, State Univ. of New York, Albany
Nussinov, Ruth, NIH & Tel Aviv Univ., Israel
Ohayon, Yoel, NYU
Olson, Wilma, Rutgers Univ.
Orozco, Modesto, Univ. of Barcelona, Spain
Osypov, Alexandr, RAS, Pushchino, Russia
Osterman, Andrei, The Burnham Institute
Ozoline, Olga., RAS, Pushchino, Moscow, Russia
Pearson, Christopher, Hospital for Sick Children, Toronto, Canada
Parker, Stephen., Boston Univ.
Peng, Chang Geng., McGill Univ.
Petersen, Michael., Univ. Southern Denmark
Phan, Anh Tuan, Memorial Sloan-Kettering
Phillips, Rob, CALTECH
Persil, Ozgul., Georgia Tech
Pierce, Niles, CALTECH
Pogozelski, Wendy., SUNY Geneseo
Potaman, Vladimir., Texas A & M Univ.
Protassevitch, Irina., Univ. of Alabama,Birmingham
Protozanova, Ekaterina., Boston Univ.
Purtov, Yu., RAS, Pushchino, Moscow, Russia
Ramachandran, Manoj, All India Institute of Med. Sci., Delhi, India
Ramirez-Alvarado, Marina, Mayo Foundation
Razga, Filip, Academy of Sciences, Czech Republic
Reich, Norbert, Univ. of California Santa Barbara
Rich, Alex, MIT
Riopel-Nelson, Shirley, Clark Univ.
Robbins, Justin, Wadsworth labs
Rogozin, Igor, NCBI/NLM/NIH
Rokita, Steve, Univ. of Maryland
Rothemund, Paul, CALTECH
Rouleau, Guy, Montreal General Hospital, Canada
Ruben, George., Dartmouth
Russu, Irina., Wesleyan Univ.
Saenger, Wolfram, Free Univ. of Berlin, Germany
SantaLucia, John., Wayne State Univ.
Sarai, Akinori., Kyushu Institute of Technology, Japan
Sarkar, Tumpa., Georgia Tech
Scheraga, Harold, Cornell Univ.
Scheraga, Mirium, Cornell Univ.
Schimmel, Paul, Scripps
Seeman, Ned, NYU
Sha, Ruojie, NYU
Sherman, William B, NYU
Shakked, Zippi, Weizmann, Rehovot, Israel
Shchyolkina, Anna, RAS, Moscow, Russia
Shih, William, Harvard Univ.
Smolina, Irina., Boston Univ.
Snyder, Tara., Wadsworth Center
Sorokin, Anatoly, RAS Pushchino, Russia
Sousa, Marcelo, Univ. of Colorado
Sponer, Jiri, Academy of Sciences, Czech Republic
Stavans, Joel, Weizmann, Rehovot, Israel
Stellwagen, Anne, Boston College
Stellwagen, Nancy, Univ. of Iowa
Stevens, Kristof., University of Gent, Belgium
Stiles, Linsey., Clark Univ.
Stoica, Ileana, NRC, Ottawa, Canada
Streltsov, Sergei., Russian Aademy of Sciences, Moscow, Russia
Strobel, Scott, Yale Univ.
Subramanian, Harikrishnan Krishnaswamy, NYU
Sugiyama, Hiroshi, Kyoto Univ., Japan
Sullivan, Michael, Hickok Cancer Res. Lab
Swanson, Maurice, Univ. of Florida
Swairjo, Manal., Scripps
Taillandier , Eliane, Univ. of Paris, Paris, France
Tainer, John, Scripps
Tajmir-Riahi, Heider-Ali., Univ. of Quebec, Canada
Thiviyanathan, Varatharasa, Univ. of Texas, Galveston
Teif, Vladimir, Balarus National Acad., Minsk, Belarus
Tolstorukov, Michael, NIH
Trifonov, Edward, Univ. of Haifa, Israel
Tullius, Tom, Boston Univ.
Tung, Chang-Shung, LANL
Ulyanov, Nick, Univ. of California, San Francisco
Uversky, Volodya, Indiana Univ., Indianapolis
Vardevanyan, Poghos., Yeravan State Univ., Armenia
Valls, Nuria, Politechnical Univ. of Catalunya, Spain
Varnai, Peter, Univ. of Cambridge, UK
Varughese, Kottayil. , Scripps
Virnik, Konstantin., NIH
Vitoc, Iulia., Wesleyan Univ.
Vologodskii, Alex, NYU
Walter, Nils G., Univ. of Michigan, Ann Arbor
Wang, Risheng, NYU
Wang, Tong, NYU
Wang, Xing, NYU
Weiss, Mike, Case Western Reserv Univ.
White, Susan, Bryn Mawr College
Widom, Jonathan, Northwestern Univ.
Wigley, Dale, Clare Hall Labs, London, UK
Wijmenga, Sybren, Univ. of Nijmegen, The Netherlands
Wu, Gang, NYU
Xu, Long., Boston Univ.
Yakovchuk, Peter., Boston Univ.
Zacharias, Martin., International Univ. of Bremen, Germany
Zakrzewska, Krystyna, IBPC, Paris, France
Zhang, Xiaoping, NYU
Zhao, J., Clark Univ.
Zheng, Jianpeng, NYU
Zheng, Jiwen, NYU
Zhong, Hong, NYU
Zhurkin, Victor, NIH
Registration, Meals & Accommodation
Abstracts: Requirements & Deadline
Young Scientist Speaker Program