Book of Abstracts: Albany 2003
June 17-21 2003
The Double Helix: A View 50 Years Later
Here, I will recount some recollections of fifty years ago when the double helix was first formulated. Many questions were asked at that time.
? How can the two coiled chains separate as they must for molecular replication?
? Can a double helix be formed by RNA? RNA was found in certain viral systems and probably needed to replicate as well.
? What was the nature of the mysterious two forms, A and B, in the diffraction patterns?
Several of these issues will be addressed, together with comments about how early knowledge was accumulated in this field.
William Thompson Sedgwick Professor of Biophysics