Conversation 10: Proceedings
Structure, Motion, Interaction and Expression of Biological Macromolecules Volumes One and Two, Hard Cover 1998
The Proceedings of the Tenth Conversation held at The University-SUNY, Albany NY, June 17-21, 1997
Editors: Sarma & Sarma
ISBN: 0-940030-76-4 Volume 1;
Just like the Conversation program, they constitute a tour de force in the discipline.
Structure, Motion, Interaction and Expression of Biological Macromolecules Volume 2
Theoretical foundations and a global overview of the known protein structures; induced conformational changes upon protein-protein association; regulatory apparatus of pp60c-Src protein; protein dynamics and NMR relaxation; structure, dynamics and function of metalloproteins.
tRNA recognition by aspartyl-tRNA synthase; RNA pseudoknots and 3D domain swaping; RNA psedoknots and RNA topoisomerase; theretical modeling of RNA 3-D structures; retroviral RNA-tetraloop substructure of the HIV-1 packaging signal; interactions of the HIV-1 rev protein with RRE RNA; structure of 5' stem-loop from human U4 snRNA; 750 MHz NMR and computer experiments on an anti-HIV-1 hammerhead ribozyme complex; ligation of hairpin ribozymes; exploration of G?U pairs in RNA by 15N NMR.
Triplet repeat genome and human diseases: trinucleotide repeat instability and slipped strand DNA; genetic control of microsatellite DNA instability; molecular dynamics of triplet repeats and mismatch pairs; molecular basis of triplet expansion; length polymorphism and gene regulation.
p53 tumor suppressor protein: DNA bending and steric constraints on conformation by p53; interactions between the p53 DNA binding domain and a DNA response element.
Volume 2, in its 296 pages, contains 23 chapters with 941 references to literature, 20 tables and 193 figures; 44 of the figures are four-color processed renditions.
Editors: Sarma & Sarma
Contents Volume 2
The Kappa-Tau Framework for Describing and Analyzing Protein Folds: Theoretical Foundations and a Global Overview of the Known Protein Structures
Molecular Surface Variability and Induced Conformational Changes Upon Protein-Protein Association
The conformational change of Tyr-248 from the unbound to the bound state in protein-protein association from Nussinov et al.
Mechanisms of Regulation in the Regulatory Apparatus of pp60c-Src
Studying Protein Dynamics with NMR Relaxation
How Does the Oxidation State of a Metalloprotein Affect its Structure, Dynamics and Function?
Enzyme-substrate Interactions in the Aspartyl-tRNA Synthetase System
The Structure of an RNA Pseudoknot Shows 3D Domain Swapping
The Construction of an RNA Knot and its Role in Demonstrating that E. coli DNA Topoisomerase III is an RNA Topoisomerase
A Reduced-Coordinate Approach to Modeling RNA 3-D Structures
Packaging and Dimer Linkage in Retroviral RNA: NMR of a GGAG-tetraloop Substructure of the HIV-1 Packaging Signal
Design and Analysis of Organic Cations that Inhibit Interactions of the HIV-1 Rev Protein with RRE RNA
Structure of the 5' Stem-Loop From Human U4 snRNA: Evidence for Destabilization of a Compact Conformation by 5-FU
Freezing-induced Self-ligation of the Hairpin Ribozyme: Cationic Effects
750 MHz NMR and Computer Experiments on an Anti-HIV-1 Hammerhead Ribozyme Complex with a 17-mer DNA Substrate Analog of HIV-1 gag RNA
Probing G·U Pairing in RNA Using 15N NMR
Studies of the Dynamics of Adenine Amino Protons in DNA by 15N-Labeling and Heteronuclear NMR Spectroscopy
Slipped Strand DNA (S-DNA and SI-DNA), Trinucleotide Repeat Instability and Mismatch Repair: A Short Review
Genetic Control of Microsatellite Instability in Saccharomyces Cerevisiae
Molecular Dynamics Simulations of DNA Molecules Containing d(GCC)n..d(GCC)n Fragments and C-C Mismatch Pairs
Toward the Understanding of the Molecular Basis of Triplet Expansion. Studies of the Single Stranded CCG and CGG DNA Trinucleotide Repeats by NMR
Structure-Function Relationship of the Insulin-Linked Polymorphic Region: Implications in Length Polymorphism and Gene Regulation
Interactions Between the P53 DNA Binding Domain and the P21/Waf1/Cip1 DNA Response Element
DNA Bending Induced by Tetrameric Binding of the p53 Tumor Suppressor Protein: Steric Constraints on Conformation