Book of Abstracts: Albany 2003
June 17-21 2003
Genomic Screens for Small RNA-encoding Genes in Escherichia coli
Small RNA (sRNA) molecules have gained lately much interest, as recent genome-wide studies have shown that they are widespread in a variety of organisms. The relatively small family of 10 known sRNA-encoding genes in Escherichia coli has been significantly expanded during the past two years with the discovery of 45 novel genes. Most of these genes are still uncharacterized and their cellular roles are unknown. In my talk I will describe the systematic identification of the sRNA-encoding genes by computational approaches and their experimental verification, as well as comparative genomic analyses attempting to characterize this unique gene family.
The Hebrew University of Jerusalem