Book of Abstracts: Albany 2009
June 16-20 2009
© Adenine Press (2008)
Genome-wide mapping and analysis of nucleosome positions in multiple human tissues
Nucleosome positioning plays a fundamental role in the regulation of the genome. To further explore the relationship between the underlying DNA sequence, chromatin architecture and genic expression in differing tissues, we have mapped nucleosome positions across three separate human tissue types from the same individual and analyzed these data in relation to the genic landscapes and regulation in these distinct cell types.
Steve M. Johnson*
Departments of Pathology and Genetics