Book of Abstracts: Albany 2003

category image Albany 2003
Conversation 13
Abstract Book
June 17-21 2003

Expanding Protein Universe and its Origin From the Biological Big Bang

The bottom up approach to understanding the evolution of organisms is by studying molecular evolution. With the large number of protein structures identified in the past decades, we discover peculiar patterns that nature imprints on protein structural space in the course of evolution. In particular, we discover that the universe of protein structures is organized hierarchically into a scale-free network. By understanding the cause of these patterns, we attempt to glance at the very origin of life.

Nikolay V. Dokholyan

Department of Biochemistry and Biophysics
University of North Carolina at Chapel Hill
School of Medicine
Campus Box 7260
Chapel Hill, NC 27599
Office: (919) 843-2513
Fax: (919) 966-2852