20th-banner-rev.png

Albany 2019: 20th Conversation - Abstracts

category image Albany 2019
Conversation 20
June 11-15 2019
Adenine Press (2019)
Showing 1 to 100 of 141 items.  Page: 1

The Structure and Dynamics of Biomolecules in Their Native States

Joachim Frank

View Abstract

Cryo-EM and drug discovery

Sriram Subramaniam

View Abstract

Deadly Spiders & Scary Zombies - NOT a Halloween Story
A near atomic resolution glance into the CNS

Moran Shalev-Benami,

View Abstract

Distance sensitive D-loop dynamics and near-atomic resolution of F-actin phalloidin structure by cryoEM

Sanchaita Das, , Peng Ge, , Zeynep A. Oztug Durer,, Elena E. Grintsevich, , Z. Hong Zhou, and , Emil Reisler, ,

View Abstract

MicroED: conception, practice and future opportunities

Tamir Gonen

View Abstract

RNA helicase activity of E. coli HflX is instrumental in rescuing heat-inactivated 23S ribosomal RNA.

Sandip Dey, Krishnamoorthi Srinivasan, Jayati Sengupta

View Abstract

Supercoiling Affects Specific Base Accessibility to Alter 3-D Shape of DNA Minicircles

Jonathan M. Fogg, Lynn Zechiedrich

View Abstract

The Conformational Landscape of the Human 26S Proteasome by Cryo-EM Structural Analysis

Rui Fang, Robin Chen , Jason Hon, Jiayi Wu , Yuanchen Dong, Yanan Zhu, Youdong Mao, Qi Ouyang, Daniel Finley , Ying Lu

View Abstract

Understanding the Functional Dynamics of the 26S Proteasome by Nucleotides-proteasome Interaction Study

Rui Fang , Ying Lu

View Abstract

Computational Design of DNA Scaffold for Optimization of CryoEM

Kendar Serindag , Kelly M. Thayer , David L Beveridge , David R. Langley

View Abstract

Effect of crown ether, 15-crown-5, on lysozyme amyloid fibrillation

Anirban Basu

View Abstract

Evaluation and validation of synergistic effect of predicted Amyloid-Beta (Aβ) inhibitor by deep neural network.

Aman Chandra Kaushik, Dong Quing Wei

View Abstract

How nature harnesses entropy to tune protein function

Zachary A. Wood , Nicholas D. Keul , Krishnadev Oruganty , Elizabeth T. Schaper Bergman , Nathaniel R. Beattie , Weston E. McDonald , Renuka Kadirvelraj , Michael L. Gross , Robert S. Phillips , Stephen C. Harvey ,

View Abstract

Intrinsically Disordered Proteins, Alternative Splicing, and Post-translational Modification (IDP-AS-PTM): A Toolkit for Developmental Biology

Keith Dunker

View Abstract

Multivalency Regulates Activity in an Intrinsically Disordered Transcription Factor

Sarah Clark, Kayla Jara, Patrick Reardon, Elisar Barbar

View Abstract

Remembering the past: A new form of protein-based inheritance

Daniel F. Jarosz

View Abstract

Seeing the structure of RNA-binding proteins in membraneless organelles and disease-associated aggregates

Nicolas Lux Fawzi

View Abstract

The Critical Role of Intrinsic Disorder in Creating Bioactive Materials

Sarah E. Bondos

View Abstract

Complex self-assembly and transformation of DNA nanostructures

Yonggang Ke

View Abstract

Designer Nucleic Acid Architectures for Programmable Self-assembly

Hao Yan

View Abstract

DNA is Not Merely the Secret of Life: Semantomorphic Chemistry in Advanced Materials

Nadrian C Seeman

View Abstract

Using DNA Origami to Decipher Spatial Effects in Biology

Björn Högberg

View Abstract

A Novel Indoline scaffold based Antibacterial Compound Designing and Pharmacological Evaluation using Chemoinformatics approach

Aarushi Singh and , Ramesh Chandra,

View Abstract

Discovery of penicillin binding proteins (PBPs) inhibitors by blending Virtual Screening, Molecular Docking and Simulation studies

Mayurpankhi Buragohain , Abha Vashishtha, Surabhi Johari

View Abstract

DNA topoisomerases as targets for antibacterial chemotherapy

Anthony Maxwell

View Abstract

Exploring peptidoglycan biosynthesis and it’s inhibition

Adrian Lloyd, Dom Bellini, Hector Newman, Christopher Dowson

View Abstract

How bacteria and cancer cells regulate mutagenesis and their ability to evolve

Susan M. Rosenberg

View Abstract

Identifying and targeting the Achilles heel of drug resistant bacteria

Nagasuma Chandra

View Abstract

Interactions of β-Lactamases with Antibiotics and Inhibitors

Catherine L. Tooke , Philip Hinchliffe , Ramya Salimraj , Karina Calvopiña , Viivi H.A. Hirvonen , Matthew B. Avison , Marc W. van der Kamp , Adrian J. Mulholland , James Spencer

View Abstract

Kinetic and Molecular Determinants of Antibiotic Permeation Barriers

Helen I. Zgurskaya

View Abstract

A comparative computational study for deamination of trans and gauche conformers of phenylethylamine in presence of lumiflavin

Subrata Dasgupta, Soumita Mukherjee, B.P. Mukhopadhyay

View Abstract

A Comprehensive Automated Computer-Aided Discovery Pipeline from Genomes to Hit Molecules .

Ruchika Bhat, Rahul Kaushik , Ankita Singh , Debarati DasGupta , Abhilash Jayaraj , Anjali Soni, Ashutosh Shandilya, Vandana Shekhar, Shashank Shekhar and, B. Jayaram

View Abstract

A fluoroamine derivative of epigallocatechin gallate exhibits both, anti-cancer and anti-tuberculosis properties. Insights from in silico and in vitro studies

Samarendra Narayanan,, K. V. Ramesh, and, Dipti Mothay,

View Abstract

A New Approach to analyze Rotavirus Transport Mechanism in Porous Media by Molecular Modelling and Molecular Dynamics methods

Elena M. Alvareda Migliaro, , Jorge Cantero, , Fernando López Tort , Matías Victoria, , Margot Paulino Zunini, , Rodney Colina and , Pablo A. Gamazo

View Abstract

Antioxidant Enzyme Catalase Activity of Rat Kidney Cells Nuclear Fraction After the Cisplatin and Estradiol Separate and Joint Action

Zhenya V.Yavroyan, Nune R. Hakobyan, Agapi G. Hovhannisyan, Gevorg A.Avagyan, Emil S. Gevorgyan.

View Abstract

“Evidence for the N-Terminal Hypothesis for Alzheimer’s Disease”

Georges Belfort

View Abstract

Calculation of protein-ligand and protein-protein binding affinities using free energy perturbation theory

Richard A. Friesner

View Abstract

Cancer Vaccine Designing and Optimization using Combined Immunoinformatics and Molecular Dynamics Simulation Approach

Neeraj Kumar and , Ramesh Chandra,

View Abstract

Carboline derivative compounds targeting DNA: Synthesis, binding and in vitro cytotoxicty on human cancer cell lines

Kakali Bhadra, Ph.D.,

View Abstract

Cisplatin and Estradiol Joint Action on Quantities of Rat Brain Chromatin Phospholipids

Nune Hakobyan, Zhenya Yavroyan, Agapi G. Hovhannisyan, Emil S. Gevorgyan,

View Abstract

Click Chemistry In Silico and Molecular Simulation Studies to Identify Novel HIV-1 Entry Inhibitor Scaffolds Targeting CD4-Binding Site of the Envelope gp120 Protein

Alexander M. Andrianov , Grigory I. Nikolaev,, , Yuri V. Kornoushenko, Alexander V. Tuzikov ,

View Abstract

Computational Design of Novel 1,2,4-Triazole-Based Compounds as Potential Aromatase Inhibitors

Alexander M. Andrianov , Grigory I. Nikolaev, Yuri V. Kornoushenko, Sergei A. Usanov ,

View Abstract

Constraining Evolution — Avoiding Drug Resistance: Lessons from Viruses

Celia Schiffer

View Abstract

De novo aggregation of Alzheimer’s Aβ25-35 peptides in a lipid bilayer

Amy K. Smith, Dmitri K. Klimov, ,

View Abstract

Dopamine Channels with Applications

Zhengqiong Zhang, , Xiaowen Zhou, , Zeren Xu, , Chengqi Lu, , Sichuan Xu

View Abstract

Elucidating the molecular interaction of Noscapine with Bovine Serum Albumin (BSA): Spectroscopic and Molecular Dynamics Approach

Chhaya Chaudhary, Damini Sood and, Ramesh Chandra,

View Abstract

Entrapment of flow of substrate to diversion pathway : strategy to combat persistent tuberculosis

Indira Ghosh

View Abstract

How the tumor suppressor p53 recognizes its DNA response elements

Dmitrij Golovenko , Oksana Degtjarik , Tali E. Haran , Haim Rozenberg , Zippora Shakked

View Abstract

Identification of Potent and Novel Phosphatidylinositol 3-Kinase Catalytic Subunit Alpha Inhibitors: A Structure-Based Drug Design Approach

Geet Madhukar, Naidu Subbarao

View Abstract

Identification of Novel Urease Inhibitors: Pharmacophore Modeling, Virtual Screening and Molecular Docking Studies .

Richa Arora, Upasana Issar & , Rita Kakkar

View Abstract

Identification of potential inhibitors for AroG against Mycobacterium tuberculosis

Nalamolu Ravina Madhulitha , Katari Sudheer Kumar, Chiranjeevi Pasala, Sivaranjani Pakala, Amineni Umamaheswari,

View Abstract

In Silico Assessment of Progesterone Receptor Ligand Binding Domain Using Molecular Dynamic: A new insight into breast cancer treatment

Vahid Zarezade, Marzie Abolghasemi, Fakher Rahim, Ali Veisi,

View Abstract

In Silico designing of Potential Noscapine Analogue and Pharmacological Evaluation using Chemoinformatics approach

Vartika Tomar, Neeraj Kumar, Ramesh Chandra,

View Abstract

In silico identification of leads targeting Interleukin-6 against pathogenesis of atherosclerosis

Kanipakam Hema , Sandeep Swargam , Natarajan Pradeep, Amineni Umamaheswari,

View Abstract

In Silico Studies of Interaction of Hoechst 33258 within Minor Groove of B-DNA .

Upasana Issar, Richa Arora, and, Rita Kakkar,

View Abstract

In-silico Assessment of Adenosine Receptor Ligand Binding Domain: A New Insight into Adenosine Receptor Based Therapeutics

Navina Panneerselvan, Radha Madendran, Malathi Rangunathan

View Abstract

Integration of binding potency estimations and stability assessments for therapeutic design against MurG of H. pylori

Pasala Chiranjeevi, Katari Sudheer Kumar, Nalamolu Ravina Madhulitha, , Sharon Priya Alexander, Amineni Umamaheswari

View Abstract

Interaction of Noscapine with Human Serum Albumin (HSA): A Spectroscopic and Molecular Modelling Approach

Heerak Chugh and, Ramesh Chandra,

View Abstract

Magnetic Resonance Spectroscopy-based metabolomics analysis of Posterior Cingulate in patients with Alzheimer’s disease: A Systematic Review Study

Kiarash Shirbandi , Mohammad Davoodi , Elmira Hosseini , Fakher Rahim , Babak Arjmand ,

View Abstract

Minimizing toxicity and maximizing the potency of bioderived compounds by synthetic fragmentation – A computational “proof-of-concept”

Fisayo A. Olotu, Geraldene Munsamy and, Mahmoud E. Soliman

View Abstract

Mutant p53 REs and the mechanism of gain of function in cancer

Jessy Safieh, Demitrij Golovenko , Tali E. Haran

View Abstract

Potent MMP-14 antagonist design through screening, docking and dynamics studies

Katari Sudheer Kumar, Pasala Chiranjeevi, Nalamolu Ravina Madhulitha, , Vankadoth Umakanth Naik, Amineni Umamaheswari

View Abstract

Scaffold hopping strategy on the route discerning novel Glutathione peroxidase agonists

Natarajan Pradeep , Katari Sudheer Kumar, Amineni Umamaheswari, Manne Munikumar , Sandeep Swargam , Kanipakam Hema, Praveen Kumar Guttula and , Mukesh Kumar Gupta

View Abstract

Structural studies on reactivation of tumor-related p53 mutants by methylene quinuclidinone (MQ), the active drug spontaneously formed from APR-246

Oksana Degtjarik , Dmitrij Golovenko , Yael Diskin-Posner , Lars Abrahmsén , Haim Rozenberg , Zippora Shakked

View Abstract

The Distribution of 3, 5, 3’-Triiodothyronine between the Transport Systems of Blood and Nuclei of the Tissues

Margarita I. Garipova, Alfira I. Shigapova, Rashit G. Farkhutdinov, Vadim V. Fedyaev, Julia M. Sotnikova, Alfira B. Yakupova

View Abstract

Using Structure To Identify Protein-Protein And Drug Protein Interaction Networks

Barry Honig

View Abstract

Applying quantitative single molecule localization microscopy to probe the mechanism of nucleocytoplasmic transport

Kathleen M. Lennon, Devin L. Wakefield, Matthew S. Brehove, Ottavia Golfetto, Sunetra Biswas, Tijana Jovanovic-Talisman

View Abstract

Self-regulating mechanisms of bi-directional transport through the Nuclear Pore Complex

T. Zheng, C. Gu, A. Zilman

View Abstract

Statistical Mechanical Model of Transport Receptor Binding in the Nuclear Pore Complex

Rob D. Coalson

View Abstract

The Nuclear Pore Complex: Paradoxes and Possibilities

Roderick Y.H. Lim

View Abstract

A ‘Double Tale’ of Evolutionary Accretion in the Structure of Biological Networks

Gustavo Caetano-Anollés, Fizza Mughal , M. Fayez Aziz

View Abstract

A Revisiting of the RESP Charge Derivation Model

Pavel Banáš , Michal Janeček , Petra Kührová , Michal Otyepka , Jiří Šponer ,

View Abstract

Evaluation of the Current State of AMBER DNA Force Fields

Marie Zgarbová , Michal Otyepka , Jiří Šponer , Petr Jurečka

View Abstract

Feature Selection in Biomolecular Models

Julie Mitchell

View Abstract

Force Fields in Trouble – What Could Our DNA and RNA Potentials Do Better?

Petr Jurečka, Marie Zgarbová , Jiří Šponer , Michal Otyepka,

View Abstract

Membranes and Machine Learning: Optimizing the transport of signals and drugs across membranes

Rachael Mansbach , Cesar A López , Paolo Ruggerone , Bridget S Wilson , Nick Hengartner , Helen I Zgurskaya , Boian Alexandrov , and S. Gnanakaran

View Abstract

Tuning the Hydrogen-bonding Interactions of the AMBER RNA Force Field

Petra Kührová , Vojtěch Mlýnský , Marie Zgarbová , Miroslav Krepl , Giovanni Bussi , Robert B. Best , Michal Otyepka , Jiří Šponer , Pavel Banáš ,

View Abstract

Ultra-fast modeling of peptide-MHC interactions with 3D Convolutional Neural Net

Mikhail Ignatov, Evangelos Coutsias , Dima Kozakov

View Abstract

Protein folding and dynamics in and out of the cytoplasm

Martin Gruebele,

View Abstract

Protein Folding Energetics and Proteostasis: A Two-Way Connection

Evan T. Powers

View Abstract

Simulations of Biomolecules in Cellular Crowded Environments

Yuji Sugita, Kento Kasahara, Hiraku Oshima, Isseki Yu, Grzegorz Nawrocki, Suyong Re, Michael Feig 2.5

View Abstract

Understanding protein behavior in cells

Gary J. Pielak

View Abstract

Effect of Insulin on DNA-Internucleosomal Fragmentation and Poly(ADP-ribose)polymerase 1 Activity in Rat Liver Nuclei

Anush Asatryan, Karine Matinyan, Irina Artsruni, Emil Gevorgyan,

View Abstract

How do DNA binding proteins interpret and modulate nucleosome dynamics ?

Vlad Cojocaru

View Abstract

Hybrid methods to characterize nucleosome structure and dynamics with high precision

Anna Panchenko

View Abstract

Investigating the structural dynamics of DNA in nucleosome core particles

Lois Pollack

View Abstract

Modeling and Informatics of DNA, Nucleosomes and Chromatin from Base Pairs to Genomes

Ran Sun, Zilong Li, Thomas C. Bishop

View Abstract

Revealing dynamic chromatin invasion by pioneer transcription factors on the single-molecule scale

Beat Fierz

View Abstract

The Effect of Tannic Acid on PARP 1 Activity and Chromatin Condensation in Rat Thymocyte and Liver Nuclei

Irina G. Artsruni , Anush L. Asatryan, Karine S. Matinyan, Emil S. Gevorgyan,

View Abstract

The Influence of Hydrocortizone and Cisplatin Co-Administration to Rats on Chromatin Olygonucleosomal Fragmentation in Liver Nuclei

Anush Asatryan, Irina Artsruni, Karine Matinyan, Emil Gevorgyan,

View Abstract

Imaging the 3D organization of the chromosome and transcriptome in single cells and the cell atlas of tissues

Xiaowei Zhuang

View Abstract

The "self-stirred" genome: Bulk and surface dynamics of the chromatin globule

Alexandra Zidovska

View Abstract

Understanding the Human genome in 3D

Leonid Mirny

View Abstract

Applications of modification detection in nanopore sequencing

Winston Timp

View Abstract

Stoichiometric Constraints in Protein Sequences

Aditya Mittal

View Abstract

Tongue tumour protein BAH14511.1 Sequence analysis and homology modelling to find out interacting binder network through molecular docking

Snigdha Singh and , Ramesh Chandra,

View Abstract

Can R-loops themselves be the mysterious R-lesions?

Elena A. Kouzminova , Andrei Kuzminov

View Abstract

Characterization of R loops in Class switch recombination

Jacqueline Barlow, Hongchang Zhao

View Abstract

Mechanisms of R-loop-induced chromosome fragility at structure-forming repeats

Xiaofeng Allen Su, Simran Kaushal, Ruby Ye , Catherine H. Freudenreich

View Abstract

Primer Handoff between DNA Primase and DNA Polymerase α

Aoshu Zhong , Lauren E. Salay , Walter J. Chazin , Jacqueline K. Barton

View Abstract
Showing 1 to 100 of 141 items.  Page: 1